A status ailment effects a party member in all three games in the Mother (series). Some ailments are realistic such as homesickness or asthma. There are only two trademark status aliments: Asthma, it is the status aliment that only Ninten receives, and Homesickness, which only Ness receives. The following is a list of other possible status ailments.

They can be categorized by types, As all status ailments do hinder the battle progress of both enemies and the player.

• Damage-Dealing Status ailments: Produces damage on a target per turn, even outside of battle.
• Stat-Decreasing Status ailments: Lowers the chances of a target from hitting, exclusively Crying.
• Restriction-Dealing Status ailments: Hinders action; some can be cured by a few turns, while others do not.

CoL, HoL, RH, and SH stand for Cup of Lifenoodles, Horn of Life, Refreshing Herb and Secret Herb, respectively.

Status	Effect	Causes	Cures
Asleep	Prevents all action.	Caused by Hypnosis.	EarthBound: CoL, HoL, RH, SH, PSI Healing. Mother 3: Alarm Cicada. Siren Beetle to awaken enemy target.
Asthma	Occasionally causes victim to miss turns during combat. Specific to Mother, only Ninten can be affected by this.	Enemy attacks such as Mad Truck's exhaust fumes.	AsthmaSpray.
Blind	Increases chance to miss with physical attacks; equivalent to crying.	Enemy attacks.	None known.
Burning	Causes damage each turn.	Possible side effect of PSI Fire.	None known.
Cold (Sniffling)	[[Mother (game)|Mother]]: Occasionally causes damage outside of combat. EarthBound: Causes about 4 damage each turn inside of combat and also occasionally while outside of combat.	Mother: Talking to people who are sick. EarthBound: Enemy attacks such as Spinning Robo's nighttime-stuffiness beam.	Mother: Mouthwash. EarthBound: CoL, HoL, RH, SH, Cold remedy, PSI Healing.
Confused	Victim may attack anyone during battle, including both allies and unintended enemy targets.	May be caused by Brainshock, BrainCyclone, Wicked seeds or Rockoyles.	Noble seeds.
Diamondized	Victim is transformed into a diamond statue and is unable to act in any way. Functions the same way as Unconscious, except that the hospital can't heal it(the blue-haired healer can).	Enemy attacks such as Trillionage Sprout's eerie stare.	CoL, HoL, SH, PSI Healing γ.
Disrupted Concentration	Prevents the use of PSI.	Enemy attacks such as Mad Duck's sense disruption.	Can't be cured. Lasts several turns.
Fleas	Occasionally prevents the victim from using special abilities such as PSI. Specific to Mother 3.	Comes from some animals.	Flea Powder.
Frozen	Prevents movement.	Possible side effect of PSI Freeze.	None known.
Homesick	Occasionally causes victim to waste a turn reminiscing about home. Specific to EarthBound, only Ness and the Mischievous Mole can be affected by this.	From not calling Ness' mother for a lengthy period of time.	Calling Ness' mother via telephone(being called via the Receiver Phone does not work), or talking to her. Temporarily cured by a chick(chicken does not work).
Mushroomized	Occasionally causes the victim to attack its allies. Also randomly changes movement controls while walking outside of battle.	Enemy attacks such as a Ramblin' Evil Mushroom's spores.	Can only be cured by a blue-haired healer, or the mushroom picking girl near a cave.
Nausea	EarthBound: Causes about 20 damage each turn. Mother 3: Prevents the victim from eating.	Enemy attacks such as Master Belch's or Stinky Ghost's burps.	EarthBound: CoL, HoL, RH, SH, PSI Healing β. Mother 3: Fresh Mint.
Numb/Paralyzed	Prevents movement. In Mother, this is equivalent to stone or unconscious; if all players are afflicted by one of these effects, the game is over.	Possible side effect of PSI Flash or PSI Thunder.	Mother: Healing β. EarthBound: CoL, HoL, SH, PSI Healing γ. Mother 3: Anti-Paralysis.
Poisoned	Causes about 20 damage each turn in EarthBound, and about 5 in Mother 3.	From naturally poisonous enemies such as snakes and arachnids.	Mother: Antidote, Healing. EarthBound: CoL, HoL, RH, SH, PSI Healing β, Vial of Serum. Mother 3: Antidote.
Possessed	A Tiny L'il Ghost follows the victim, which, on each turn, will either do an insignificant amount of damage or solidify someone. Specific to EarthBound.	Enemy attacks such as Zombie Possessor's icy hand.	Receiving an attack that damages the entire party(such as PSI Fire); the ghost itself can take damage.
PSI Block	Prevents the use of PSI. Specific to Mother; however, EarthBound has an equivalent ailment, disrupted concentration.		Can't be healed. Lasts until the battle ends.
Puzzled	Victim occasionally wastes turns daydreaming.	Caused by the attacks of Titanian, Woodoh, and Kelly.	Can't be healed. Lasts until the battle ends.
Solidified	Prevents movement, but not PSI.	Enemy attacks, such as Coil Snake's coil.	Can't be cured, but only lasts one turn.
Stone	Prevents all action. Equivalent to unconsciousness or paralysis; if all players are afflicted by one of these effects, the game is over. Specific to Mother.	StoneOrigin.	Healing γ.
Strangeness	Occasionally causes the victim to attack its allies.	Possible side effect of PSI Flash, certain effect of Brainshock.	EarthBound: CoL, HoL, RH, SH, PSI Healing β.
Stuck	Equivalent to paralysis, also counts as unconscious. However, it will heal after a few turns. Specific to Mother.		Can't be cured. Lasts several turns.
Sunstroke	Causes 4 damage every turn.	From being in the desert for some period of time.	CoL, HoL, RH, SH, Wet Towel, PSI Healing.
Unconscious (Fainted)	Prevents all action. If all characters are in an unconscious state, the game is over.	From being reduced to 0 HP.	Mother: Super Healing. EarthBound: CoL, HoL, SH, PSI Healing γ, hospitals. Mother 3: Hot Spring
Uncontrollable crying	Greatly increases chance to miss with physical attacks(but not PSI).	Possible side effect of PSI Flash or various enemy attacks such as a Mad Taxi's exhaust fumes.	EarthBound: CoL, HoL, RH, SH, PSI Healing β. Mother 3: Eye drops

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