"These mounds emit a toxic stink that can blind even the most rugged hero. Use PSI Fire."
EarthBound Player's Guide

Slimy Little Piles are enemies in EarthBound, and are located inside Master Belch's factory. They have counterparts in the game, Mini Barfs and Even Slimier Little Piles. They mainly just burp at Ness and his friends, causing them to cry and lowering their accuracy.